This product(s) resides on a APICMO contract.
We have the ability to produce, synthesize and manufacture large quantities of Tetrahydro-4H-pyran-4-one(29943-42-8) with quality control system under CGMP manufacturing regulations.
Tetrahydro-4H-pyran-4-one(29943-42-8) is employed in the preparation of 4-methoxytetrahydropyran-4-yl protecting group, synthesis of symmetric tetra substituted methanes. The methyl enol ether is a useful protecting agent for alcohols, e.g. in nucleotide synthesis, with the advantage over 3,4-Dihydro-2H-pyran. It is also employed in a study of the enantioselective alpha-aminoxylation of ketones with nitrosobenzene and L-proline in an ionic liquid. It undergoes condensation reactions in the preparation of dipeptides and spiroimidazolones. It is also employed in wittig reactions for the synthesis of Penicillins and in a ring of vitamin D3
Novel amphiphilic poly(2-oxazoline)s bearing L-prolinamide moieties at the alkyl side-chain termini were designed and synthesized by a bottom-up protocol. These polymers formed micelle-type assemblies with a size of 10–30 nm in water, in which the majority of prolinamide active groups was tucked into the hydrophobic inner core. As a nanoreactor, the micellar systems were successfully applied to the direct asymmetric aldol reaction in aqueous media. The results demonstrated that the polymer-bound prolinamide catalysts show a significant improvement in catalytic efficiency when compared with their monomeric counterpart and non-amphiphilic reference polymer, affording the anti-product with a moderate stereoselectivity in the representative aldol addition of cyclohexanone to p-nitrobenzaldehyde. Additionally, the poly(2-oxazoline) derivatives can also promote effectively the reactions of Tetrahydro-4H-pyran-4-one(29943-42-8) or cyclopentanone donors to give the corresponding aldol adducts in high yield and with good diastereo- and enantioselectivities.
|CAS Min %||95%|
|CAS Max %||100%|
|Chemical Name or Material||Tetrahydro-4H-pyran-4-one|
|Molecular Weight (g/mol)||100.117|
|Color||Colorless through Yellow|
|Melting Point||165° to 167°C|
Tetrahydro-4H-pyran-4-one(29943-42-8)Safety and Handling
(29943-42-8)GHS H Statement
- Combustible liquid.
(29943-42-8)GHS P Statement
- Keep away from heat/sparks/open flames/hot surfaces. – No smoking.
- Wear protective gloves/protective clothing/eye protection/face protection.
- In case of fire: Use for extinction: CO2, powder or water spray.
- Store in a well-ventilated place. Keep cool.
- Dispose of contents/container in accordance with local/regional/national/international regulations.
WARNING: The information provided on this web site was developed in compliance with European Union (EU) regulations and is correct to the best of our knowledge, information and belief at the date of its publication. The information given is designed only as a guide for safe handling and use. It is not to be considered as either a warranty or quality specification.
Novel amphiphilic poly(2-oxazoline)s bearing L-prolinamide moieties as the pendants: Synthesis, micellization and catalytic activity in aqueous aldol reaction
Novel amphiphilic poly(2-oxazoline)s bearing L-prolinamide moieties at the alkyl side-chain termini were designed and synthesized by a bottom-up protocol.
Polymer (United Kingdom) 2016
Novel tetrahydropyran-based bacterial topoisomerase inhibitors with potent anti-gram positive activity and improved safety profile
Novel antibacterial drugs that are effective against infections caused by multidrug resistant pathogens are urgently needed.
Journal of Medicinal Chemistry 2015
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Tetrahydro-4H-pyran-4-one(29943-42-8)Bulk Ordering & Pricing:
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