Morpholin-3-one (109-11-5)
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The ability to produce, synthesize and manufacture large quantities of Morpholin-3-one (109-11-5) with quality control system under CGMP manufacturing
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Description
3-ketomorpholine is also known as morpholin-3-one, 3-morpholone;3-MORPHOLINONE;MORPHOLIN-3-ONE;3-Oxomorpholine;3-Ketomorpholine;morpholine-3-one. It is useful pharmacological intermediate. Recent studies have shown that some morpholin-3-one derivatives could effectively cause cell cycle arrest at G1 phase, increase the levels of P53 and Fas, and induce A549 cell apoptosis in lung cancer. This indicates it might be a useful tool for elucidating the molecular mechanism of lung cancer cell apoptosis and might also be potential anti-cancer drugs. Some of its derivatives have been proven to be useful for the prevention and treatment of arteriosclerosis and hypertriglyceridemia.
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Morpholin-3-one (109-11-5) Specifications
| CAS | 109-11-5 |
| CAS Min % | 98.0 |
| CAS Max % | 100.0 |
| MDL Number | MFCD00631009 |
| InChI Key | VSEAAEQOQBMPQF-UHFFFAOYSA-N |
| Chemical Name or Material | Morpholin-3-one |
| Infrared Spectrum | Authentic |
| Physical Form | Solid |
| Packaging | bottle |
| Molecular Formula | C4H7NO2 |
| Molecular Weight (g/mol) | 101.105 |
| SMILES | C1COCC(=O)N1 |
| Color | Off white to slight yellow |
| Melting Point | 106.0° to 108.0°C |
| Assay | 98% |
Morpholin-3-one (109-11-5) Safety and Handling
(109-11-5) GHS H Statement
- Harmful if swallowed.
- Harmful in contact with skin.
- Harmful if inhaled. Causes skin irritation.
- May cause an allergic skin reaction.
- Causes serious eye damage.
- May cause respiratory irritation.
Morpholin-3-one GHS P Statement
- Wear protective gloves/protective clothing/eye protection/face protection.
- IF ON SKIN: Wash with plenty of soap and water.
- IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
- IF INHALED. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or doctor/physician.
WARNING: The information provided on this web site was developed in compliance with European Union (EU) regulations and is correct to the best of our knowledge, information and belief at the date of its publication. The information given is designed only as a guide for safe handling and use. It is not to be considered as either a warranty or quality specification.
Morpholin-3-one (109-11-5) Articles
He, Q., et al. “Novel morpholin-3-one derivatives induced apoptosis and elevated the level of P53 and Fas in A549 lung cancer cells.”
Bioorganic & Medicinal Chemistry 15.11(2007): 3889.
Murai, Hiromu, et al. “Morpholinone derivatives and method of use.”
US, US4237132. 1980.
Gonzalez-garcia, Maria Rosario, and Fernandez, Maria Carmen.
“Morpholinyl derivatives useful as MOGAT-2 inhibitors.” (2015).
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