2,4-Dichloro-1H-pyrrolo[2,3-d]pyrimidine (90213-66-4)

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SKU: 90213-66-4 Category:


2,4-Dichloro-1H-pyrrolo[2,3-d]pyrimidine (90213-66-4) Specifications

CAS 90213-66-4
CAS Min % 98%
CAS Max % 100%
MDL Number MFCD08059278
Chemical Name or Material 2,4-dichloro-7H-pyrrolo[2,3-d]pyrimidine
Infrared Spectrum Authentic
Physical Form Crystalline Solid
Packaging Glass bottle
Molecular Formula C6H3Cl2N3
Molecular Weight (g/mol) 188.01
Color Off-white
Melting Point 248.9-251.3°C
Assay ≥98%

Applications: It is used as a pharmaceutical intermediate.

Solubility: Soluble in DMSO, ethyl acetate and methanol. Slightly soluble in water.

Notes:Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.


2,4-DICHLORO-7H-PYRROLO2,3-DPYRIMIDINE;2,6-Dichloro-7-deazapurine;2,6-dichloro-7-deazapurin ;2,4-DICHLORO-7H-PYROLO-[2,3-D]PYRIMIDINE;4,6-DICHLORO PURINE;2,4-Dichloro-1H-pyrrolo[2,3-d]pyrimidine;2,4-Dichloro-7H-pyrrolo[2…;7H-Pyrrolo[2,3-d]pyriMidine,

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2,4-Dichloro-1H-pyrrolo[2,3-d]pyrimidine (90213-66-4) Safety and Handling

APICMO hazard icons

(90213-66-4) Hazard description:

♦ Causes skin irritation

♦ Causes serious eye irritation.

♦ May cause respiratory irritation

Precautionary statement:

♦ Avoid breathing dust/fume/gas/mist/vapours/spray.

♦ If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. If eye irritation persists: Get medical advice or attention.

♦ If in hand: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

WARNING: The information provided on this web site was developed in compliance with European Union (EU) regulations and is correct to the best of our knowledge, information and belief at the date of its publication. The information given is designed only as a guide for safe handling and use. It is not to be considered as either a warranty or quality specification.

2,4-Dichloro-1H-pyrrolo[2,3-d]pyrimidine (90213-66-4) Articles

7-Deaza Isosters of 2′-Deoxyxanthosine and 2′-Deoxyspongosine – Synthesis via Glycosylation of 2,4-Dichloro-7H-pyrrolo<2,3-d>pyrimidine

Compound 5a was obtained by glycosylation of 2,4-dichloro-7H-pyrrolo<2,3-d>pyrimidine (3b) with the halogenose 4.Due to the reactivity of the chromophore halogens removal of the toluoyl residues by sodium methoxide resulted in rapid displacement of the chloro substituents which prevented the isolation of the free deoxyriboside of 3b and led to the 2,4-dimethoxynucleoside 7.

Liebigs Annalen der Chemie 1985

Synthesis of 4-chloro-7H-pyrrolo[2,3-d]pyrimidine and 2,4-dichloro-7H- pyrrolo[2,3-d]pyrimidine

An efficient route to synthesize 4-chloro-7H-pyrrolo[2,3-d;]pyrimidine (6) and 2,4-dichloro-7H-pyrrolo[2,3-d]pyrimidine (10) starting from diethyl malonate in five steps with the total yields of 45.8percent and 44.8percent was disclosed in the presented paper.

Chinese Journal of Organic Chemistry 2010

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