2,4-Dichloro-pyrimidine-5-carboxylic acid ethyl ester (51940-64-8)

This product(s) resides on a APICMO contract.

The ability to produce, synthesize and manufacture large quantities of 2,4-Dichloro-pyrimidine-5-carboxylic acid ethyl ester (51940-64-8) with quality control system under CGMP manufacturing
regulations.

Category:

Description

Applications

It′s employed as an important intermediate for raw material for organic synthesis, agrochemical, pharmaceutical and dyestuff field

Solubility

Slightly soluble in water.

Notes

Store in cool, dry place in tightly closed container. With adequate ventilation. Store away from oxidizing agent.

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2,4-Dichloro-pyrimidine-5-carboxylic acid ethyl ester (51940-64-8) Specifications

CAS 51940-64-8
CAS Min % 97.5
CAS Max % 100.0
MDL Number MFCD09910281
InChI Key SRJBDGLSCPDXBL-UHFFFAOYSA-N
Chemical Name or Material 2,4-Dichloro-pyrimidine-5-carboxylic acid ethyl ester
Infrared Spectrum Authentic
Physical Form Powder
Packaging Glass bottle
Molecular Formula C7H6Cl2N2O2
Molecular Weight (g/mol) 221.037
SMILES CCOC(=O)C1=CN=C(N=C1Cl)Cl
Color White
Melting Point 36° to 37°C
Assay 98%

 

2,4-Dichloro-pyrimidine-5-carboxylic acid ethyl ester (51940-64-8) Safety and Handling

(51940-64-8) Hazard description:APICMO hazard icons

◆Causes skin irritation.

◆Causes serious eye irritation.

◆May cause respiratory irritation.

2,4-Dichloro-pyrimidine-5-carboxylic acid ethyl ester Precautionary statement:

◆Avoid breathing dust/fume/gas/mist/vapors/spray.

◆Wear protective gloves/protective clothing/eye protection/face protection.

◆IF IN EYES: Rinse cautiously with water for several minutes.

◆Remove contact lenses, if present and easy to do.

◆Continue rinsing.

◆IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.

◆Store locked up.

◆Dispose of contents/container in accordance with local/regional/national/international regulations.

WARNING: The information provided on this web site was developed in compliance with European Union (EU) regulations and is correct to the best of our knowledge, information and belief at the date of its publication. The information given is designed only as a guide for safe handling and use. It is not to be considered as either a warranty or quality specification.

2,4-Dichloro-pyrimidine-5-carboxylic acid ethyl ester (51940-64-8) Articles

Pharmaceutical raw materials 2, 5 – difluoro – 6 – ethyl purine – 5 – carboxylic acid methyl ester (by machine translation)

The invention relates to a medicine raw material 2, 5 – difluoro – 6 – ethyl purine – 5 – carboxylic acid methyl ester, to purine carboxylic acid as the raw material, in the solvent methanol and catalyst under the action of vanadium pentoxide, temperature 125 °C – 155 °C through the esterification reaction, the ethylization and fluorine substitution reaction to produce 2, 4 – dichloro – 6 – methyl pyrimidine – 5 – carboxylic acid methyl ester….

AAS Medicinal Chemistry Letters 2018 vol. 8 # 11 p. 1226 – 1228,

Synthesis, characterization, and in vitro evaluation of the selective P2Y2 receptor antagonist AR-C118925

The Gq protein-coupled, ATP- and UTP-activated P2Y2 receptor is a potential drug target for a range of different disorders, including tumor metastasis, inflammation, atherosclerosis, kidney disorders, and osteoporosis, but pharmacological studies are impeded by the limited availability of suitable antagonists…

Purinergic Signalling 2017 vol. 13 # 1 p. 89 – 103,

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