5-Bromopyrimidine (4595-59-9)

(2 customer reviews)

This product(s) resides on a APICMO contract.

The ability to produce, synthesize and manufacture large quantities of 5-Bromopyrimidine (4595-59-9) with quality control system under CGMP manufacturing



2-chloro-5-aminopyrimidine (56621-90-0) video

5-Bromopyrimidine was used in the synthesis of N-heteroaryl substituted 9-arylcarbazolyl derivatives via palladium-catalyzed aerobic and ligand-free Suzuki reaction, (5-(phenylethynyl)pyrimidine) via microwave assisted organic synthesis (MAOS) Sonogashira protocol.

This product(s) resides on a APICMO contract. If you are viewing this page as a non-registered user, the price(s) displayed is List Price. To view your pricing, log in using your account number, or become a registered user by contacting one of our Customer Service teams. To place an order, contact APICMO Customer Service.

5-Bromopyrimidine (4595-59-9) Specifications

CAS 4595-59-9
CAS Min % 97.5
CAS Max % 100.0
MDL Number MFCD00006117
Chemical Name or Material 5-Bromopyrimidine
Assay Percent Range 98%
Physical Form Solid
Packaging Glass bottle
Molecular Formula C4H3BrN2
Molecular Weight (g/mol) 158.986
Color White-Yellow
Melting Point 69.0° to 73.0°C
Assay 98%

5-Bromopyrimidine (4595-59-9) Safety and HandlingAPICMO hazard icons

(4595-59-9) Hazard description:

  • Causes serious eye irritation.
  • Causes skin irritation.

5-Bromopyrimidine Precautionary statement:

IF ON SKIN: Wash with plenty of soap and water.

Wear protective gloves/protective clothing/eye protection/face protection.

IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

WARNING: The information provided on this web site was developed in compliance with European Union (EU) regulations and is correct to the best of our knowledge, information and belief at the date of its publication. The information given is designed only as a guide for safe handling and use. It is not to be considered as either a warranty or quality specification.

5-Bromopyrimidine (4595-59-9) Articles

A rosuvastatin calcium impurities in the intermediate preparation method (by machine translation)

The invention discloses a preparation method for a rosuvastatin calcium intermediate impurity. The preparation method comprises: by taking formaldehyde and [4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-methanesulfonamino)-5-pyrimidyl] triphenylphosphonium bromide as raw materials…

Xie Yongju; Gong Jie 2018

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

5-Bromopyrimidine (4595-59-9)Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications? 


2 reviews for 5-Bromopyrimidine (4595-59-9)


    APICMO has a fantastic ability to synthesize and produce chemical products in large scale, among them being 5-Bromopyrimidine (4595-59-9). This product has been manufactured with high-tech equipment, quality products, and high-class expertise ensuring that it meets all the rules and regulations of CGMP manufacturing and quality control system.

    5-Bromopyrimidine (4595-59-9) description

    There has been a study to understand the displacement reactions of 5-bromopyrimidine with nucleophiles under microwave irradiation. This chemical undergoes direct metallation with lithium diisoprypylamide resulting in 4-lithio-f-bromopyrimidine.

    5-Bromopydrimidine is used in the synthesis of N-heteroaryl subtitured 9-arylcarbazolyl derivatives through palladium-catalyzed aerobic plus ligand-free Suzuki reaction. This product resides in Apicmo contract and you can, therefore, feel free to learn more about it and order from them.

    5-Bromopydrimidine application

    It is used in the synthesis of;

    • (5-(phenylelethynyl) pyrimidine) via microwave-assisted organic synthesis Sonogashira protocol
    • N-hereroaryl substituted 9-arylcarbazolyl derivatives y palladium-catalyzed aerobic and ligand-free Suzuki reaction

    5-Bromopydrimidine chemical structure

    5-Bromopyrimidine (4595-59-9)

    5-Bromopyrimidine (4595-59-9) product specification

    CAS NO 4595-59-9
    Chemical name 5-Bromopyrimidine
    Boiling point (˚C) 168
    Flash point (°C) 98
    molecular formula C4H3BrN2
    Molecular weight 158.986 g/mol
    Monoisotopic mass 157.948 g/mol
    Physical state Solid
    Purity 98%
    Color White yellow
    Density 1.6448
    Structural formula 5-Bromopyrimidine (4595-59-9)
    Synonyms 5-pyriMidine;5-bromo-pyrimidin
    5 – broMine pyriMidine

    5-Bromopydrimidine chemical, physical properties

    This chemical is soluble in chloroform

    4595-59-9 bonding

    Hydrogen bond acceptor count 2
    Hydrogen bond donor count 0
    Rotatable bond count 0

    4595-59-9 appearance

    The chemical is an off-white solid

    5-Bromopyrimidine (4595-59-9) computed properties

    Covalently-Bonded Unit Count 1
    Isotope Atom Count 0
    Undefined Bond Stereo center Count 0
    Defined Bond Stereo center Count 0
    Undefined Atom Stereo center Count 0
    Defined Atom Stereo center Count 0
    Heavy Atom Count 7
    Compound Is Canonicalized True
    Formal Charge 0
    XLogP3 0.7
    Topological Polar Surface Area 25.8 A^2
    Exact Mass 157.948 g/mol
    Complexity 51.7

    5-Bromopyrimidine (4595-59-9) synthesis route

    This chemical has five synthesis routes as follows;

    5-Bromopyrimidine (4595-59-9)

    5-Bromopyrimidine precursor and product downstream


    5-Bromopyrimidine (4595-59-9)

    Product downstream

    5-Bromopyrimidine (4595-59-9)

    5-Bromopyrimidine (4595-59-9)

    Uses of 5-Bromopyrimidine

    It is used in;

    • The synthesis of (5-(phenylelethynyl) pyrimidine) via microwave-assisted organic synthesis Sonogashira protocol
    • Synthesizing process of N-hereroaryl substituted 9-arylcarbazolyl derivatives y palladium-catalyzed aerobic and ligand-free Suzuki reaction

    Dangers associated with 5-Bromopyrimidine

    GHS classification symbol

    APICMO hazard icons

    • The chemical may cause eye irritation if it comes to contact with your eyes which could eventually lead to permanent damage if not attended to
    • It leads to skin irritation and allergies which could end up in soreness and redness
    • In a case of ingestion, the product causes diarrhea and vomiting
    • It can harm the respiratory tract if inhaled

    5-Bromopyrimidine safety measures and personal protection

    Never forget to put on protective gears before you start working with 5-Bromopyrimidine. Get heavy gloves, a face mask and go for one with air filters, eyeglasses, and appropriate footwear. This is to ensure that the product does not come into direct contact with any parts of your body.

    1. 5-Bromopyrimidine (4595-59-9) engineering control

    Your laboratory or working area should be equipped with safety and emergency equipment. These include fire extinguishers, air cleaners, vapor compressor, fume hood, safety shower and taps with running water. That is not all; ensure that it is well ventilated with adequate moving air.

    2. 5-Bromopyrimidine (4595-59-9) first aid measures

    Sometimes, it could be your unlucky day, and regardless of careful you are when handling this product, it ends up coming into contact with your skin. What measures should you take?

    • In a case of inhalation

    The victim should be taken outside the lab immediately to an open space or an area with adequate ventilation. If the individual is experiencing hardships when breathing, administer artificial respiration before rushing them to a medical professional.

    • If ingested

    If the chemical accidentally gets into the mouth, the affected person should start by rinsing the mouth thoroughly with lots of water followed by drinking about half a liter of water. You should however never try to induce vomiting.

    • Eye contact

    Immediately rush to tap with lots of running water and rinse your eyes for approximately 10 to 15 minutes. Do not forget to remove lenses if you have them on for easier cleaning and if irritation persists, see a doctor.

    • Skin contact

    Quickly rush to the tap and rinse the affected area with plenty of water and a mild cleanser. If you got a lot of spillages, go the safety shower have your body clean ensuring that you put on clean clothes. Reuse the damaged garments only after washing them.

    3. 5-Bromopyrimidine (4595-59-9) storage

    Store the chemical at room temperature to prevent decomposition. Also, make sure that the container is tightly closed and also, keep it at a safe place to avoid access by unauthorized users. Always use its original container for storage.

    4. How do you handle 5-Bromopyrimidine (4595-59-9)?

    Take the following measures when working with 4595-59-9;

    • Avoid inhaling vapor, mist or dust
    • Work from a well-ventilated space with enough with enough safety equipment
    • Make sure that you put on protective clothes such as gloves, masks, and glasses

    5. Things to do after working with 4595-59-9

    • Immediately go to the tap and clean your hands thoroughly before heading to the shower and cleaning your entire body
    • Put on clean clothes and wash the working garments
    • Dispose the empty containers and any residues. Ensure to dispose them following the state’s rules and regulations.
    • Store the remainder chemical safely as per the regulations

    6. Accidental measures

    What happens in the event of accidents in the lab?


    Use absorbent material to soak up the spilled product before disposing it in a waste container. Ensure to ventilate the area and use a vapor compressor to get rid of strong fumes and vapor.

    7. 5-Bromopyrimidine (4595-59-9) stability

    This chemical is stable as long as it is kept under the ideal pressure and temperature, oxidizing agents and acids.

    8. 5-Bromopyrimidine (4595-59-9) waste disposal

    This product should be treated as special waste, and you should, therefore, be cautious when getting rid of it. Follow the local, federal and international rules and regulations ensuring that it does not land on unauthorized hands.

    9. 4595-59-9 shipping info

    The chemical is stable and can, therefore, be transported by air or sea in bulk without causing any harm.

    Regulatory information

    Follow all the local, state and international rules and regulations in all the stages of working with this chemical.

    Technical info

    All our staff are well trained and have extensive experience in matters concerning products synthesis, chemical analysis, chromatography, life, and material science.

    5-Bromopyrimidine (4595-59-9) pricing and bulk ordering

    Are you in need of this product for manufacturing, research or development? Then feel free to make bulk orders from us.


    1. National Centre For Biotechnology Information, US. National Library Of Medicine, Pubchem,5-Bromopyrimidine, Sections 1-10.
    2. Jie Jack Li, Gordon W. Gribble, Palladium in Heterocyclic Chemistry: A Guide for the Synthetic Chemist, page 200-210.
    3. Desmond J. Brown, John Wiley & Sons, The Pyrimidines, 15 Sep 2009, page 209-212.

  2. Apicmo

    The best 5-Bromopyrimidine and service i have ever had,Nice experience

Add a review

Your email address will not be published.