4-Bromo-2-fluoropyridine (128071-98-7)

(2 customer reviews)

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4-Bromo-2-fluoropyridine (128071-98-7) video

The pyridine compound is one of the most widely developed varieties of heterocyclic compounds. 4-Bromo-2-fluoropyridine is one of the pyridine compounds and is also an excellent intermediate for an important fine chemical raw material. It Harmful if swallowed, also causes skin irritation and causes serious eye irritation. So, be careful when you use it.

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4-Bromo-2-fluoropyridine (128071-98-7) Specifications

CAS 128071-98-7
CAS Min % 95.0
CAS Max % 100.0
MDL Number MFCD04112504
Chemical Name or Material 4-Bromo-2-fluoropyridine
Assay Percent Range 97%
Physical Form Powder or Chunks
Packaging Glass bottle
Molecular Formula C5H3BrFN
Molecular Weight (g/mol) 175.988
Color Colorless through Yellow
Melting Point 65.0°C (5.0 Torr)

4-Bromo-2-fluoropyridine (128071-98-7) Safety and HandlingAPICMO hazard icons

(128071-98-7) Hazard description:

  • Toxic in contact with skin.
  • Combustible liquid.
  • Harmful if swallowed.
  • Harmful if inhaled.
  • Causes skin irritation.
  • Causes serious eye irritation.
  • May cause respiratory irritation

4-Bromo-2-fluoropyridine Precautionary statement:

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

WARNING: The information provided on this web site was developed in compliance with European Union (EU) regulations and is correct to the best of our knowledge, information and belief at the date of its publication. The information given is designed only as a guide for safe handling and use. It is not to be considered as either a warranty or quality specification.

4-Bromo-2-fluoropyridine (128071-98-7) Articles

Arylboronic Acids

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Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

4-Bromo-2-fluoropyridine (128071-98-7) Bulk Ordering & Pricing:

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2 reviews for 4-Bromo-2-fluoropyridine (128071-98-7)


    Avoid the trouble of ordering chemical products and receiving a different quality from what you ordered. Instead, use our services to guarantee youhigh quality at a competitive price. At APICMO, we manufacture a variety of chemical products including 4-Bromo-2-fluoropyridine (128071-98-7).All our products conform to the Common Good Manufacturing Practice (CGMP) and other manufacturing regulations. Buy from us today and experience our excellent service.

    4-Bromo-2-fluoropyridine (128071-98-7) Chemical Structure

    4-Bromo-2-fluoropyridine (128071-98-7)

    4-Bromo-2-fluoropyridine (128071-98-7) Synthesis route

    4-Bromo-2-fluoropyridine (128071-98-7)

    4-Bromo-2-fluoropyridine (128071-98-7) Precursor and Downstream products


    4-Bromo-2-fluoropyridine (128071-98-7)

    Downstream Products

    4-Bromo-2-fluoropyridine (128071-98-7)

    4-Bromo-2-fluoropyridine (128071-98-7) Synonyms

    • 4-Bromo-2-fluoropyridine
    • 128071-98-7
    • 2-Fluoro-4-bromopyridine
    • Pyridine, 4-bromo-2-fluoro
    • 4-bromo-2-fluoro-pyridine
    • -Bromo-2-fluoropyridine
    • 98% broMo-4 fluoro-2 pyridine Pyridine
    • 4-broMo-2-fluoro-4-Bromo-2-fluoropyridine

    4-Bromo-2-fluoropyridine (128071-98-7) Product Specifications

    Purity 98%
    Physical State Liquid
    Monoisotopic Mass g/mol 174.943
    Molecular Weight g/mol 175.988
    Molecular Formula C5H3BrFN
    Melting Point ˚c 65.0 (5.0Torr)
    Density 1.707 g/cm^3
    Chemical Name 4-Bromo-2-fluoropyridine
    Boiling Point ˚c 195 at 760 mmHg
    CAS no 128071-98-7
    Flash Point ˚c 71

    4-Bromo-2-fluoropyridine (128071-98-7) Chemical and Physical Properties


    It is a light yellow liquid.


    Covalent 1
    Rotatable 0
    Hydrogen Acceptor-2


    4-Bromo-2-fluoropyridine (128071-98-7) is stable under normal conditions. It, however, decomposes under high temperature to produce;

    • Hydrogen fluoride
    • Nitrogen oxides (NOx)
    • Carbon monoxide and carbon dioxide
    • Hydrogen bromide

    4-Bromo-2-fluoropyridine (128071-98-7) Computed Properties

    Property Name Property Value
    Isotope Atom Count 0
    Undefined Bond Stereocenter Count 0
    Defined Bond Stereocenter Count 0
    Undefined Atom Stereocenter Count 0
    Defined Atom Stereocenter Count 0
    Heavy Atom Count 8
    Formal Charge 0
    Compound Is Canonicalized True
    XLogP3-AA 2
    Exact Mass 174.943 g/mol
    Topological Polar Surface Area 12.9 A^2
    CACTVS Substructure Key Fingerprint AAADcQBiAQAAEAAAAAAAAA
    Complexity 78.8

    4-Bromo-2-fluoropyridine (128071-98-7) Uses

    • Used as an organic reagent.
    • Used as a pharmaceutical intermediate.

    Hazards associated with 4-Bromo-2-fluoropyridine (128071-98-7)APICMO hazard icons

    • It is toxic once ingested. It may cause drowsiness, vomiting/nausea, stomach pains or discomfort and loss of appetite.
    • It may irritate the respiratory tract once inhaled. It could lead to; a dry cough, chest pain, shortness of breath, the inability to breath.
    • It may cause severe eye damage once it splashes into your eyes. The symptoms may be; pain or intense burning, tearing profusely, bleeding and reddening.
    • It may cause skin irritation once it comes into contact with your skin.

    4-Bromo-2-fluoropyridine (128071-98-7) Safety Measures

    1. Personal Protection

    Skin/Body protection

    Ensure that you wear a protective garment that is selected based on the hazards that are present at the workplace, the duration of chemical product use, physical environment,etc. Chooseprotective clothingmade of a suitable fabric that doesn’t react with the substance. At the minimum, you should be in close-toed shoes and a laboratory coat.

    Hands Protection

    Always wear gloves when handling this chemical product. Select gloves that are of high quality. The gloves should be selected based on an assessment done on the possible hazards on skin and hands,the physical conditions of the workstation, the duration you’ll use the chemical product and the chemical resistance of the glove material. Ensure that you inspect the gloves before use to ensure that there are no tears that could allow the permeation of the substance. Remove the glove using the proper technique and without touching the outer surface to protect you from getting into contact with the chemical product. Dispose of the gloves properly, wash your hands and dry them.

    Eye/Face Protection

    Put on safety goggles that are tightly fitting. The safety glasses should have a minimum of the 8-inch face shield. Always use tested and approved eye protection equipment under appropriate government standards,i.e., EN 166 (EU), NIOSH (US)

    Respiratory Protection

    In case a risk assessment shows that air-purifying respirators are suitable, use (US) or type ABEK (EN 14387) respirator cartridges.Always use tested and approved respirators and components under appropriate governments,i.e., CEN (EU), NIOSH (US)

    2. 4-Bromo-2-fluoropyridine (128071-98-7) Engineering Controls

    • Equip the facility with eye baths and safety showers for cleaning up in case of an accident. They should be ten seconds close to the workstation to ensure prompt response to any exposure.
    • Use sufficient general and local exhaust ventilation to contain dust and fumes produced in your operations.

    3. First aid Measures


    In case one inhales the substance, move them to an area that has fresh air. Place them in a position that they can breathe comfortably. If the victim is not breathing, administer oxygen. Seek the advice of a physician.


    If the chemical product splashes into your eyes, immediately flush your eyes with plenty of water for a minimum of 15 minutes. Keep your eyes wide open while doing it and do not forget to clean under both eyelids. If irritation persists, obtain the attention of a doctor immediately.


    If it gets into contact with your skin, immediately remove any contaminated shoes and clothes. Clean the surface with a lot of water and mild soap for a minimum of 15 minutes. Wash the contaminated clothes and allow them to ventilate before reusing them. Seek the advice of a doctor.


    If a victim ingests the substance, rinse the mouth with water. You should not try to induce vomiting without the advice of a doctor. Do not give an unconscious victim anything through the mouth. See a doctor immediately.

    Rescuers should ensure that they are in personal protective equipment,i.e., CPR masks and gloves if necessary.

    4. When using 4-Bromo-2-fluoropyridine (128071-98-7)

    Keep away from ignition sources; open flames, hot surfaces, heat, and sparks due to its combustible nature. Avoid breathing the dust, fumes,andvapors produced while using the substance because they might irritate your respiratory system. Do not eat, drink or smoke anything to avoid poisoning. Ensure that you wear all the protective equipment that is necessary while using this chemical product. Use the substance only when in an area with sufficient ventilation or outdoors to prevent accumulation of fumes. Ensure that you have first aid equipment, safety showers,eyebaths, and spillage equipment close to you to avoid a response delay in the event of an accident. Make sure that all containers are well-labeled while using them.

    5. After Using 4-Bromo-2-fluoropyridine (128071-98-7)

    Dispose of all containers properly as soon as you can because they may be a hazard. Take off all protective wear, clean it and let it ventilate for some time before wearing it again. Wash your hands thoroughly even if you were in gloves. Ensure you do it before consuming anything or visiting the washrooms. Dry your hands with a clean towel to avoid recontamination. Clean up the working surface to prevent any slipping hazards.

    6. When out of use

    Keep all the containers containing the substance tightly capped to avoid spillage.Label all the bottlesfor easier identification. Do not place the containers on bench tops to preventknock-offs. Place the substancein a cool place that has adequate ventilation and far from strong oxidizing agents. Prevent access to unauthorized personnel toprevent accidents.

    7. 4-Bromo-2-fluoropyridine (128071-98-7) Handling and Storage


    Avoid any skin or eye exposure by wearing protective gear to prevent irritation. Do not inhale the mist/ vapor. Keep away from any sources of ignition,i.e. smoking, sparks. Follow the practices that could help you prevent the build-up of electrostatic charge. Minimize the generation and accumulation of dust. Always ensure that you open and handle containers with care. Do not smoke/eat/or drink anything while working with this chemical product.


    Store the chemical product in a cool and dry area that has adequate ventilation. Keep the container upright and tightly closed; all opened containers must be resealed to prevent the substance from spilling. Store the chemical product away from other combustible liquids and sources of fire.

    8. 4-Bromo-2-fluoropyridine (128071-98-7) Accidental Measures


    Prevent any further spillage if it is possible and safe to do so. Do not allow the substance to get into drains, soil,and other waterwaysbecause it may be a contaminant. Make sure that all uninvolved persons do not get into the spillage scene. Ensure that the ventilation is sufficient.

    Contain the spillage and then collect it with an electrical protected vacuum cleaner. You can also collect it by wet-brushing or absorbing it with a material that is inert andplace it in a suitable waste container ready for disposal in adherenceto the local laws.


    In case of a fire ask everyone at the working area to move into a safe place. Transfer any portable storage containers away from the scene if it is safe and easy to do so. Ensure that you wear all protective gear. Use any of the following extinguishing media;

    • Dry chemical
    • Carbon dioxide
    • Water spray
    • Alcohol-resistant foam

    To cool the unopened containers use water spray.

    Hazardous fumes emitted during combustion are; Hydrogen fluoride, Hydrogen bromide gas, Nitrogen oxides (NOx) and carbon oxides. A firefighter is therefore advised to wear a breathing apparatus that is self-contained.

    9. Sensitivity and Reactivity

    4-Bromo-2-fluoropyridine (128071-98-7) reacts with strong oxidizing agents. It is highly combustible,and you should, therefore, avoid the following conditions; heat, sparks,and flames. The hazardous gases produced upon combustion are;Hydrogen fluoride, Hydrogen bromide gas, Carbon oxides and Nitrogen oxides (NOx).

    10. Chemical Disposal

    You can burn this chemical product in a chemical incinerator that has a scrubber and an afterburner. You are advised to take great caution while igniting it due to its combustible nature. You could also offer surplus and non-recyclable solutions to a waste disposal company that is licensed.Dispose of any contaminated packaging as an unused product.

    11. Shipping Information

    4-Bromo-2-fluoropyridine (128071-98-7) is safe to transport by road, air and water transport.

    4-Bromo-2-fluoropyridine (128071-98-7) Bulk Pricing and Ordering

    Are you interested in ordering 4-Bromo-2-fluoropyridine (128071-98-7)?  Contact our interactive customer service for any inquiries that you may have.


    1. Pyridine and its Derivatives, Supplement, Part 2, edited by R. A. Abramovitch, Page 430
    2. Halogenated Heterocycle Synthesis, Application, and Environment, edited by JemejIskra, Alicia Decker, Page 210
    3. National Safety News, National Safety Council, American Society of Safety Engineers, Cornell University, 8thAugust 2011, Page 64 and 65
  2. Apicmo

    The best 4-Bromo-2-fluoropyridine and service i have ever had,Nice experience

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