1 review for 2-Chloropyrimidine-5-carboxylic acid (374068-01-6)

1. 

   APICMO – 12/10/2018

   Could you be searching for a reliable chemical synthesizing company? Look no further. APICMO has proven its worth and incredible ability when it comes to the production of chemicals including 2-chloropyrimidine-5-carboxylic acid (374068-01-6) also referred to as 2-–chloro-pyrimidine carboxylic acid. We can synthesize and produce it in large quantities, observing all the rules and regulations of CGMP and meeting the requirements of the quality control system.

   2-chloropyrimidine-5-carboxylic acid description

    (374068-01-6) chemical structure

   

   2-chloropyrimidine-5-carboxylic acid (374068-01-6) product specification

   CAS NO	374068-01-6
   Chemical name	2-chloropyrimidine-5-carboxylic acid
   Density	1.58g/cm 3
   IUPAC name	2-chloropyrimidine-5-carboxylic acid
   Flashpoint(ºC )	202.612
   Melting point	125.0° to 127.5°C
   Boiling point	411.407ºC at 760 mmHg
   Infrared Spectrum	Authentic
   Molecular Formula	C5H3ClN2O2
   Chemical Name or Materia	2-Acetylphenylboronic acid
   Physical Form	Powder or Crystalline Powder
   Molecular Weight (g/mol)	158.54
   SMILES	C1=C(C=NC(=N1)Cl)C(=O)O
   Synonyms	Z1741971255 Q-103422 103-0337 068C016 2-chloropyrimidine-5-carboxylic acid,AldrichCPR C-1718W5829 FT-0601815 FT-0083582 AM20090600 2-CHLORO-5-PYRIMIDINYLCARBOXYLIC ACID TC-068575 ST1140989 DB-01321 2-chloropyrimidine-5-Carboxylic Acid 374068-01-6 2-Chloro-pyrimidine-5-carboxylic acid 2-Chloro-5-carboxypyrimidine 5-Pyrimidinecarboxylicacid, 2-chloro- 2-CHLORO-5-PYRIMIDINECARBOXYLIC ACID 5-PYRIMIDINECARBOXYLIC ACID, 2-CHLORO- 2-Chloropyrimidine-5-carboxylicacid

   2-chloropyrimidine-5-carboxylic acid (374068-01-6) chemical and physical properties

   This product is a crystalline powder

   Hydrogen bonding

   Rotatable bond count	1
   Hydrogen bond donor count	1
   Hydrogen bond acceptor count	4

    

   374068-01-6 computed properties

   Covalently-Bonded Unit Count	1
   Isotope Atom Count	0
   Defined Bond Stereocenter Count	0
   Undefined Bond Stereocenter Count	0
   Defined Atom Stereocenter Count	0
   Undefined Atom Stereocenter Count	0
   Heavy Atom Count	10
   Formal Charge	0
   Compound Is Canonicalized	True
   XLogP3-AA	0.7
   Monoisotopic Mass	157.988 g/mol
   Topological Polar Surface Area	63.1 A^2
   Complexity	134
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   2-chloropyrimidine-5-carboxylic acid uses

   This product is used as a pharmaceutical intermediate

   Hazards associated with 2-chloropyrimidine-5-carboxylic acid

   GHS classification symbol

   

   If it comes into contact with your skin, this chemical could result to;

   • Skin irritation and allergies which could end up into soreness, redness, and inflammation
   • Eye irritation once it comes into contact with your eyes. This problem could become permanent damage if not handled appropriately
   • It could result in irritation in the respiratory tract if inhaled
   • It leads to vomiting and diarrhea in the event of ingestion

   2-chloropyrimidine-5-carboxylic acid safety measures and personal protection

   When working with this chemical, you have to protect your body fully to ensure that it does not come into direct contact with your skin.

   Skin protection

   • Put on long-sleeved clothes to protect your hands
   • Wear heavy protective gloves
   • Ensure to put on the appropriate footwear

   Eyes

   • Put on protective glasses to ensure that the product does not come into contact with your eyes

   Respiratory protection

   • Ensure to put on a dust mask to ensure that you do not inhale the product’s dust or fumes
   • Choose a mask with air filters
   • Make sure that the mask covers the mouth area too to avoid accidental ingestion

   1. 2-chloropyrimidine-5-carboxylic acid (374068-01-6) engineering control

   Your working space should be well ventilated and well-equipped with the necessary safety devices and measures. These include fire extinguisher, fume hood, safety shower, taps with running water and air cleaning equipment.

   2. First aid measures

   When working with 2-chloropyrimidine-5-carboxylic acid, things could go wrong, and you could accidentally expose your body to the chemical. This comes in handy with some risks, and you, therefore, need to take immediate measures to put things under control. In such cases, administer the following first aid measures;

   skin contact

   Rush to the tap and rinse the affected area with a lot of water and non-abrasive soap. If your clothes got the spillage too, it is best if you take off the damaged clothes and put on clean ones

   Eye contact

   Rinse your eyes with running water for about 15 minutes. If irritation persists, do not hesitate to seek medical assistance.

   Inhalation

   The victim should be taken outdoors or transferred to a well-ventilated room with lots of fresh air. If s/he is having breathing difficulties, administer artificial oxygen before rushing them to a healthcare center.

   Ingestion

   In the event of accidental swallowing, the victim should rinse his/her mouth thoroughly with a lot of clean water. If s/he is unconscious, avoid administering anything through the mouth. Also, note that you should never induce vomiting.

   3. 2-chloropyrimidine-5-carboxylic acid storage

   • Ensure to store this chemical with its original container
   • Store it in a cool, dry place
   • The container should be tightly closed and ensure that there are no leaks
   • Lock it in a safe place away from any unauthorized access
   • Do not keep it near other products that could promote decomposition

   4. Precautions when using 2-chloropyrimidine-5-carboxylic acid

   When working with this chemical, you need to be extra cautious to avoid any accidents.

   • Do not inhale its fumes, mist or vapor
   • Ensure that your working area is adequately ventilated
   • Your laboratory should be equipped with safety and emergency equipment which include fire extinguisher, vapor compressor, fume hood, air cleaner, taps with running water and a safety shower

   5. After using 2-chloropyrimidine-5-carboxylic acid

   Safety measures do not end at using the chemical. You need to observe them even after you are done working by;

   • Cleaning the working area and get rid of any empty containers and residue. Make sure to dispose them following the rules and regulations of your state
   • Store the remaining product appropriately
   • Observe your hygiene by washing your hands first, take a shower, put on clean clothes and wash the clothes you had on when working

   6. 2-chloropyrimidine-5-carboxylic acid accidental cases

   Spillage

   If you accidentally spill the chemical, do not panic. Take an absorbent material and soak the spilled product. Toss it in a waste container. Wash the area with plenty of water and do not forget to ventilate air for adequate air movement. Use a vapor compressor to minimize its vapor and remember, your body should be well protected while doing this.

   7. Stability

   This chemical is very stable but only when used and stored under the appropriate pressure and temperature. Avoid using it with other chemicals that could cause decomposition, such as strong acids and oxidizing agents.

   8. 374068-01-6 waste disposal

   You should treat this product as special waste and therefore observe the local, federal and international rules and regulations when disposing it. Also, you can opt to burn it in an incinerator for further safety.

   9. Shipping details

   Based on the fact that the chemical is stable, it can be shipped in bulk without the fear of any dangers.

   2-chloropyrimidine-5-carboxylic acid regulatory information

   All the information provided in this article is correct as per our knowledge, and it was developed in compliance with European Union regulations. It is meant to be a guide for safety when handling and using the chemical.

   Always observe all your local and federal rules and regulations when using, storing and disposing the chemical.

   Technical information

   Our technicians are dedicated to offering the best of best chemicals. They excel in all areas concerning chemical research, synthesis, production, life science, material science, chemical analysis, and chromatography.

   2-chloropyrimidine-5-carboxylic acid bulk ordering and pricing

   Note that this product is meant for research, development, and manufacturing. If you require this chemical in bulk for any of these purposes, feel free to order with us.

   Bibliography

   1. National Centre For Biotechnology Information, US. National Library Of Medicine, PubChem 2-chloropyrimidine-5-carboxylic acid (374068-01-6) Sections 1-10.
   2. H. Rodd, Elsevier Pub. Co., 1960 – Chemistry, Organic, Chemistry of Carbon Compounds: pt. A. Heterocyclic compounds. pt. B. Heterocyclic compounds. pt. C. Heterocyclic compounds. pt. E. Heterocyclic compounds, page 2136.
   3. H. Rodd, Elsevier Publishing Company, 1951, Carbon compounds, Chemistry of Carbon Compounds: pt. A General introduction and aliphatic compounds. pt. B. Aliphatic compounds, page 1293-1294.