Methyl 6-bromo-3-oxo-3,4-dihydropyrazine-2-carboxylate (21874-61-3)
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Description
Methyl 6-bromo-3-oxo-3,4-dihydropyrazine-2-carboxylate (21874-61-3) Description
Methyl 6-bromo-3-oxo-3,4-dihydropyrazine-2-carboxylate is an intermediate typically in the synthesis of Methyl 6-bromo-3-oxo-3,4-dihydropyrazine-2-carboxylate commercially named Favipiravir, which is a unique viral RNA Polymerase inhibitor for the treatment of Influenza (potentially treat the novel coronavirus pneumonia), acting on viral genetic copying to prevent its reproduction. A practical and step-economic route to Favipiravir. The complete synthesis of favipiravir from 2-aminopyrazine.
Favipiravir was approved for marketing in Japan in March 2014 and used for antiviral treatment of influenza A and B. In addition to the influenza virus, the drug also showed good antiviral activity to a variety of RNA viruses, such as Ebola virus, sand virus, Bunia virus.
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Methyl 6-bromo-3-oxo-3,4-dihydropyrazine-2-carboxylate (21874-61-3) Specifications
| CAS | 21874-61-3 |
| MDL Number | MFCD28405860 |
| InChI Key | HHFMFCVOODVACN-UHFFFAOYSA-N |
| Chemical Name or Material | methyl 3-hydroxy-6-bromopyrazine-2-carboxylate; HHFMFCVOODVACN-UHFFFAOYSA-N; 3-methoxycarbonyl-5-bromopyrazine-2-one;DA-43217; FT-0749179; methyl 6-bromo-3-hydroxy-2-pyrazinecarboxylate |
| Infrared Spectrum | Authentic |
| Physical Form | Powder |
| Packaging | Aluminum Foil Bag |
| Molecular Formula | C6H5BrN2O3 |
| Molecular Weight (g/mol) | 173.999 |
| SMILES | COC(=O)C1=NC(=CNC1=O)Br |
| Color | White powder |
| Melting Point | 233.0195 |
| Assay | 98% |
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