Tert-Butyl 1-Oxa-6-azaspiro[2.5]octane-6-carboxylate (147804-30-6)

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Description

tert-Butyl 1-Oxa-6-azaspiro[2.5]octane-6-carboxylate (147804-30-6) video

Tert-Butyl 1-Oxa-6-azaspiro[2.5]octane-6-carboxylate is spiro compound. Spiro compound has as protein kinase inhibitors, including as c – Met the activity of tyrosine kinase inhibitors and the like, and can be used for the treatment of these kinase of diseases caused by abnormal activity, such as cancer, or for the preparation of a medicament for treating these diseases.

Its Chemical describption is 1-oxa-6-aza-spiro-[2.5]octane-6-caboxylic acid tert-butyl ester, tert-Butyl 1-oxa-6-azaspiro[2.5]octane-6-carboxylate, 6-aza -6-tert-butyloxycarbonyl-1-oxaspiro<2.5>octane, 1-oxa-6-aza-spiro[2,5]octane-6-carboxylic acid tert-butyl ester, 1-oxa-6-aza-spiro[ 2.5]octane-6-carboxylic acid tert-butyl ester, 1,1-dimethylethyl 1-oxa-6-azaspiro[2.5 ]octane-6-carboxylate, 1,1-dimethylethyl 1-oxa-6-azaspiro[2.5]octane -6-carboxylate.

It is used as a pharmaceutical intermediate. It is also used as an intermediate in organic syntheses.

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tert-Butyl 1-Oxa-6-azaspiro[2.5]octane-6-carboxylate (147804-30-6) Specifications

CAS 147804-30-6
CAS Min % 95.0
CAS Max % 98.0
MDL Number MFCD07779385
InChI Key ULSBMKGFFFMGOI-UHFFFAOYSA-N
Chemical Name or Material tert-butyl 1-oxa-6-azaspiro[2.5]octane-6-carboxylate
Infrared Spectrum Authentic
Assay Percent Range 97%
Physical Form Crystalline Powder
Packaging Glass bottle
Molecular Formula C11H19NO3
Molecular Weight (g/mol) 213.277
SMILES CC(C)(C)OC(=O)N1CCC2(CC1)CO2
Color White
Chemical Name or Material tert-Butyl 1-Oxa-6-azaspiro[2.5]octane-6-carboxylate
Melting Point 56° to 58°C
Assay ≥96.0%

 

tert-Butyl 1-Oxa-6-azaspiro[2.5]octane-6-carboxylate (147804-30-6) Safety and Handling

(147804-30-6) Hazard description:

Causes skin irritation.

Causes serious eye irritation.

May cause respiratory irritation.

Avoid breathing dust/fume/gas/mist/vapors/spray.

tert-Butyl 1-Oxa-6-azaspiro[2.5]octane-6-carboxylate Precautionary statement:

Avoid breathing dust/fume/gas/mist/vapours/spray.

Wear protective gloves/protective clothing/eye protection/face protection.

IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

IF INHALED: Remove to fresh air and keep comfortable for breathing. Store locked up.

Dispose of contents/container in accordance with local/regional/national/international regulations.

WARNING: The information provided on this web site was developed in compliance with European Union (EU) regulations and is correct to the best of our knowledge, information and belief at the date of its publication. The information given is designed only as a guide for safe handling and use. It is not to be considered as either a warranty or quality specification.

tert-Butyl 1-Oxa-6-azaspiro[2.5]octane-6-carboxylate (147804-30-6) Articles

Nafizal Hossain

Nafizal Hossain, et al. Spirocyclic compounds, potent CCR1 antagonists.Bioorg. Med. Chem. Lett.,2013

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