N-Boc-azetidine-3-carboxylic acid (142253-55-2)

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Description

N-Boc-azetidine-3-carboxylic acid (142253-55-2) video

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N-Boc-azetidine-3-carboxylic acid. It belongs to intermediates category. Contact us for more information.

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N-Boc-azetidine-3-carboxylic acid (142253-55-2) Specifications

CAS 142253-55-2
CAS Min % 95.0
CAS Max % 100.0
MDL Number MFCD01860897
InChI Key NCADHSLPNSTDMJ-UHFFFAOYSA-N
Chemical Name or Material 142253-55-2;1-Boc-azetidine-3-carboxylic acid; 1-N-Boc-3-Azetidinecarboxylic acid; N-boc-azetidine-3-carboxylic acid; Boc-azetidine-3-carboxylic acid; 1-(tert-Butoxycarbonyl)azetidine-3-carboxylic Acid
Infrared Spectrum Authentic
Physical Form Crystalline Powder
Packaging Sealed foil bag
Molecular Formula C9H15NO4
Molecular Weight (g/mol) 201.222 g/mol
SMILES CC(C)(C)OC(=O)N1CC(C1)C(=O)O
Color White
Melting Point 103.0-107.0°C
Assay 98%

N-Boc-azetidine-3-carboxylic acid (142253-55-2) Safety and HandlingAPICMO hazard icons

(142253-55-2) Hazard description:

  • Harmful if swallowed
  • Causes skin irritation
  • Causes serious eye irritation
  • May cause respiratory irritation

N-Boc-azetidine-3-carboxylic acid Precautionary statement:

Avoid breathing dust/fume/gas/mist/vapours/spray.

WARNING: The information provided on this web site was developed in compliance with European Union (EU) regulations and is correct to the best of our knowledge, information and belief at the date of its publication. The information given is designed only as a guide for safe handling and use. It is not to be considered as either a warranty or quality specification.

N-Boc-azetidine-3-carboxylic acid (142253-55-2) Articles

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1 review for N-Boc-azetidine-3-carboxylic acid (142253-55-2)

  1. APICMO

    Do you need a supply of large or small quantities of N-Boc-azetidine-3-carboxylic acid 142253-55-2? Look no further, we at APICMO produces, synthesizes, and manufactures the highest quality of 142253-55-2 among many other chemicals.

    With us, you are sure to get superior products as we comply with all CMPG regulations on quality control as well as other laws and regulations on manufacturing. N-Boc-azetidine is of the azetidine category.

    What are Azetidines?

    Azetidines are very rare liquid heterocyclic compounds which are used to dissolve substances including the pharmaceutical products.

    N-Boc-azetidine-3-carboxylic acid 142253-55-2 Synonyms

    There are several names all referring to one product the same CAS number 142253-55-2. They include;

    • Boc-aze(3)-oh
    • 1-n-boc-azetidine-3-carboxylic acid
    • Azetidine-1,3-dicarboxylic acid mono-tert-butyl-ester
    • 1-tert-butoxycarbonyl azetidine-3-carboxylic acid
    • 1-(t-butoxycarbonyl)azetidine-3-carboxylic acid
    • 1-(tert-butoxycarbonyl)-3-azetidine carboxylic acid
    • Azetidine-1,3-dicarboxylic acid-1-tert-butyl ester
    • 1-boc-azetidine 3-carboxylic acid
    • Azetidine-3-carboxylic acid, n-boc protected
    • 3-carboxyazetidine-1-carboxylic acid tert-butyl ester
    • N-(tert-butoxycarbonyl)azetidine-3-carboxylic acid
    • Boc-3-azetidine carboxylic acid
    • 1-Boc-3-azetidinecarboxylic acid
    • N-boc-3-azetidine carboxylic acid
    • 1-[(2-methylpropan-2-yl0oxycarbonyl]azetidine-3-carboxylic acid
    • 1-Boc-azetidine-3-carboxillic acid
    • 1-Boc-3-azetidine-3-carboxylic acid
    • Boc-3-azetidinecarboxylic acid
    • 1-Boc-3-azetidine carboxylic acid
    • Boc-N-azetidine-3-carboxylic acid
    • 1-t-butoxycarbontyazetidine-3-carboxylic acid
    • 1-(tert-butoxycarbonyl)azetidine-3-carboxylic acid
    • 1-(t-butoxycarbonyl)-azetidine-3-carboxylic acid
    • 3-carboxyazetidine-1 carboxylic acid tert-butyls
    • 1-(t-butoxycarbonyl)-3-azetidinecarboxylic acid
    • 1-(tert-butyloxycarbonyl)azetidine-3-carboxylic acid
    • 142253-55-2 1-(tert-butoxycarbonyl)azetidine-3-carboxylic acid
    • 1-[(tert-butyl)oxycarbonyl]azetidine-3-carboxylic acid
    • 1-Boc-azetidine-3-carboxylic acid, >98% (TLC)
    • 1-(tert-butoxycarbonyl)-3- azetanecarboxylic acid
    • 1-(tertiary butoxy carbonyl)azetidine-3-carboxylic acid
    • 1-tert butyloxycarbonyl-azetidine-3-carboxylic acid
    • 1-[(tert-butoxy)carbonyl]azetidine-3-carboxylic acid
    • Boc-azetidine-3-carboxylic acid
    • 1-(tert-butoxycarbonyl)azetidine-3-carboxylic acid
    • N-boc-azetidine-3-carboxylic acid
    • 1-N-boc-3-azetidecarboxylic acid
    • 1-boc-azetidine-3-carboxylic acid

    N-Boc-azetidine-3-carboxylic acid 142253-55-2 Applications

    142253-55-2 is used for manufacturing of substances and laboratory chemicals.

    N-Boc-azetidine-3-carboxylic acid 142253-55-2 Structural Formula

    N-Boc-azetidine-3-carboxylic acid (142253-55-2) -APICMO Azetidines

    N-Boc-azetidine-3-carboxylic acid 142253-55-2 Chemical and Physical Properties

    Having a molecular formula of C9H15NO4, N-Boc-azetidine-3-carboxylic acid 142253-55-2 has a molecular weight of 201.222 g/mol and an exact mass of 201.1 g/mol.

    142253-55- 2 has a density of 1.246 g/cm3, with a vapour pressure of 6.35 E-0.5 mmHg at 25degree Celsius and a flash point of 147.9 degree Celsius.

    N-Boc-azetidine-3-carboxylic acid has a melting point ranging from 101.1-101.9 degree Celsius with a boiling point of 321 degree Celsius at 760 mmHg.

    N-Boc-azetidine-3-carboxylic acid  appears as white to light pale yellow crystalline powder and has a purity of 97%.

    N-Boc-azetidine-3-carboxylic acid 142253-55-2 Computed Properties

    Property Name Property Value
    Covalently-Bonded Unit Count 1
    Isotope Atom Count 0
    Undefined Bond Stereocenter Count 0
    Defined Bond Stereocenter Count 0
    Undefined Atom Stereocenter Count 0
    Defined Atom Stereocenter Count 0
    Heavy Atom Count 14
    Formal Charge 0
    Compound Is Canonicalized Yes
    XLogP3-AA 0.4
    Monoisotopic Mass (g/mol) 122.028
    Topological Polar Surface Area 66.8 A^2
    CACTVS Substructure Key Fingerprint AAADccByOAAAAAAAAAAAAAA
    AAABYAAAAAAAAAAAAAAAAA
    AAAAAAAHAAACAAADUTBg
    AQCCABgAIAACQGAAAAAAAAA
    AAAAEIAAAAAAgAAAAMQAACBg
    AAAAAAAAAAAAAAAAAAAAAAAA
    AAAAAAAAAAAAAAAA==
    Complexity 250
    Rotatable Bond Count 3
    Hydrogen Bond Acceptor Count 4
    Hydrogen Bond Donor Count 1

    N-Boc-azetidine-3-carboxylic acid 142253-55-2 Synthesis Route

    N-Boc-azetidine-3-carboxylic acid (142253-55-2)

    N-Boc-azetidine-3-carboxylic acid 142253-55-2 Potential Health Hazards

    Ingestion

    N-Boc-azetidine-3-carboxylic acid 142253-55-2 may be harmful if ingested as it may irritate the digestive tract system.

     

    Contact

    N-Boc-azetidine-3-carboxylic acid 142253-55-2 may irritate the skin if there is direct contact since it may be absorbed through the skin.

    Any contact of N-Boc-azetidine-3-carboxylic acid 142253-55-2 with eyes may cause eye irritation.

    Inhalation

    142253-55-2 may irritate the respiratory tract upon inhalation.

    N-Boc-azetidine-3-carboxylic acid 142253-55-2 Safety Measures

    First Aid Measures

    Contact

    Direct contact of N-Boc-azetidine-3-carboxylic acid with eyes may result in serious eye irritation or eye damage. Cautiously flush the eyes with plenty amount of running water for about 15 minutes.  As you do this, occasionally lift the upper and the lower eyelids to wash out as much chemical as possible.

    If in contact lenses and are easy to remove, do so as you continue flushing. Get to a health facility for medical attention.

    If in contact with the skin, wash the affected skin generously with plenty amount of water using a mild soap. Remove any contaminated clothing and shoes as you continue cleaning. Remember to wash the contaminated clothes and shoes before you reuse them.

    Inhalation

    If a victim breathes N-Boc-azetidine-3-carboxylic acid 142253-55-2, remove from exposure. Bring the victim to a place with fresh air or a well-ventilated room.

    In case breathing is difficult or has stopped give artificial respiration. Do not attempt mouth-to-mouth resuscitation for a chemical victim.

    Ingestion

    In case one swallows N-Boc-azetidine-3-carboxylic acid 142253-55-2, generously rinse the mouth with plenty amount of water. If the victim is unconscious, do not give anything orally but bring the victim to the hospital.

    N-Boc-azetidine-3-carboxylic acid 142253-55-2 Engineering Controls

    Follow general safe industrial engineering hygiene and good laboratory practices when handling 142253-55-2. Ensure you provide exhaust ventilation to places where there is dust formation.

    N-Boc-azetidine-3-carboxylic acid 142253-55-2 Personal Protection

    Handling

    Avoid generating and accumulating dust and ensure you provide exhaust ventilation to areas where dust is formed. Avoid breathing gas, mist or vapors when handling 142253-55-2. Respiratory protection equipment is not necessary for this product; use type P1 (EN 143) or type N95 (US) dust mask for nuisance dust levels. These should meet CEN (EU) or NIOSH) (US) government standards.

    Wear gloves when handling this product; the gloves must be inspected before use. When removing the gloves use the suitable technique; do not touch the exteriors of the contaminated gloves to avoid direct contact. Use to good laboratory practices and applicable laws when disposing of N-Boc-azetidine-3-carboxylic acid 142253-55-2.

    For body protection, choose the protective equipment depending on the chemical type, its concentration and the danger of the substances involved; these should be specific for any particular workplace.

    Wear appropriate eye protection equipment that is tested and approved by government standards like EN 166 (EU) or NIOSH (US).

    Do not eat, drink or smoke when handling N-Boc-azetidine-3-carboxylic acid 142253-55-2.

    Take regular measures to prevent a fire when handling N-Boc-azetidine-3-carboxylic acid 142253-55-2.

    N-Boc-azetidine-3-carboxylic acid 142253-55-2 Storage

    Keep this product in a tightly closed container; store in a place that is cool and dry and has adequate ventilation.

    Store this product away from any incompatible materials such as strong oxidizing agents.

    N-Boc-azetidine-3-carboxylic acid 142253-55-2 Disposal Method

    Offer any surplus solutions that are non-recyclable to a licensed waste disposal firm. Do not discharge 142253-55-2 into water drains, sewer lines or the environment.

    Spillage/leakage

    Sweep up and use a shovel to collect then place in a closed container ready for disposal.

    N-Boc-azetidine-3-carboxylic acid 142253-55-2 Fire Fighting Measures

    Possible special hazardous products emanating from 142253-55-2 substance or mixture include; Nitrogen Oxides, and Carbon Oxides.

    In the event of a fire involving 142253-55-2 either alone or with other materials; use alcohol-resistant foam, Carbon Dioxide, water spray, and dry chemical to put off the fire. Do not use water jets and straight streams to fight this fire. Wear the appropriate protective equipment when fighting the fire which should have a self-contained breathing apparatus.

    Technical Service

    At APICMO, we have a team of scientists who are excellent and have experience in Life Science, Chromatography, Material Science, Chemical Synthesis and Analysis among others.

    N-Boc-azetidine-3-carboxylic acid 142253-55-2 Bulk Ordering and Pricing

    Are you in need a supply of large quantities of N-Boc-azetidine-3-carboxylic acid 142253-55-2 with high quality and standard? Get to us through our team of dedicated and friendly customer care and place your order. We will surely exceed your expectation on our delivery.

    Bibliography

    1. Bioorganic and Medicinal Chemistry Letters, , vol. 12, # 5 p. 757 – 76.
    2. National Centre For Biotechnology Information, US. National Library Of Medicine, Pubchem,N-Boc-azetidine-3-carboxylic acid 142253-55-2, Sections 1-9.
    3. Gordon W. Gribble, John A. Joule, Newnes, 13 Dec 2012,  Science, Progress in Heterocyclic Chemistry, Volume 24, page 34-36.
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